A Breakthrough in Cellular Imaging

KIC® merges fast videography with high-throughput analytics, analyzing thousands of individual cells simultaneously to detect even the subtlest therapeutic effects - whether curative or toxic.

Slow Motion for Deeper Insight

By recording cellular events at up to 1,500 frames per second, KIC® can replay millisecond-scale action potentials in stunning slow motion to unveil previously invisible biological processes.

Precision Data at Scale

Powered by CyteSeer® analysis software, KIC® extracts hundreds of functional activity and morphological measurements per cell, revealing cellular heterogeneity often masked in traditional whole-field imaging.

• 7,000 wells screened daily (96/384-well plates)
• 10,000x more optical data than standard cytometry
• 4 billion cell health data points collected per day

KIC® Key Features:

• Fast Image Acquisition - 100 fps standard configuration
• Optional: Ultra-Fast Imaging - up to 1500 fps
• Sensitive Camera – High-resolution, low noise
• Hybrid Auto Focus – Failproof precision
• Solid-State Light Sources – Stable & bright
• Optional: Multi-Mode Stimulation – Electrical, Optical, Chemical
• Optional: Environmental Control – CO₂, temperature, hypoxia

Why Single-Cell Analysis Matters

Traditional whole-field imaging obscures critical details by averaging results, leading to missed insights. KIC® + CyteSeer® technology captures the unique behavior of individual cells.

Single-cell Video Analysis for Unparalleled Precision

CyteSeer® transforms raw video data into high-resolution cellular insights, using speed-optimized algorithms to:

• Identify & segment every individual cell
• Extract & quantify each transient event
• Parameterize cellular kinetics with unparalleled accuracy

Big Data, Simplified

CyteSeer® processes an unprecedented volume of cellular data:

• 4 billion parameters on 3-10 million cells analyzed daily
• 77 TB of video from up to 7,000 wells screened per day
• 10-20 million cellular activity response measurements per drug test

KIC® + CyteSeer®: Unlock Transformative Insights for Drug Discovery

By combining CyteSeer®’s advanced video analysis - which transforms KIC® video into rich single-cell data - with Vala’s deep expertise in data interpretation, drug developers gain access to highly predictive, actionable insights.

• Detect subtle therapeutic effects with exceptional sensitivity
• Analyze complex human mixed-cell & organoid disease models
• Measure critical cell-to-cell interactions, including synaptic communication

⚠️ Note: CyteSeer® is not available as standalone software - it is exclusively available for Vala imaging systems.

High-Resolution Imaging at Unmatched Speed & Value

Vala’s Structured Illumination Microscopy (ValaSIM™) delivers confocal-level resolution at high-throughput drug screening speeds without compromise.

Why ValaSIM™?

• Best-in-Class Resolution – Matches top confocal microscopes
• Fast Imaging – Speeds rival lower-resolution systems
• Minimal Phototoxicity – Preserves cell health for longer studies
• Compact & Easy to Use – The smallest footprint in its class
• Affordable – Half the price of competing technologies

Unlike other imaging systems that sacrifice speed for resolution (or vice versa), ValaSIM™ delivers both - making it the ultimate tool for scientists who demand clarity, efficiency, and affordability.

KIC® + ValaSIM™: Next-Level 3D Imaging

Integrating ValaSIM™ with KIC® unlocks advanced 3D imaging with:

• Confocal-equivalent resolution (delivers sharp, in-focus images)
• High signal-to-noise improves image clarity and contrast
  
• Lowest phototoxicity (for live-cell imaging applications)
• Z-stacking to reconstruct and visualize 3D volumes
  
• Plate scanning speeds on par with spinning disk systems

Powerful, Precise, Accessible

From neuronal synapses to brain organoids, ValaSIM™ enhances high-throughput drug discovery and biological assays by capturing high-resolution images.